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Clinical Nursing Research, Vol. 14, No. 3, 273-293 (2005)
DOI: 10.1177/1054773805275122

Sleep Disturbance and Depression as Barriers to Adherence

Kenneth D. Phillips

University of South Carolina

Linda Moneyham

University of South Carolina

Carolyn Murdaugh

University of Arizona

Mary R. Boyd

University of South Carolina

Abbas Tavakoli

University of South Carolina

Kirby Jackson

University of South Carolina

Medha Vyavaharkar

University of South Carolina

This study examined the relationships among subjective sleep disturbance, depressive symptoms, and adherence to medications among HIV-infected women. HIV-infected women ( N = 173) were recruited through community AIDS service organizations throughout South Carolina. Participants completed the Pittsburgh Sleep Quality Index (PSQI), the Centers for Epidemiological Studies Depression Scale (CES-D), and a modified version of the Adults AIDS Clinical Trials Group Adherence Baseline Questionnaire. Women who reported greater sleep disturbance also reported a higher level of depressive symptoms and reported poor adherence to their medication regimen. Depression helped to explain the relationship between sleep quality and adherence. Results indicate that assessment and management of sleep disturbance and depressive symptoms in women with HIV disease is important to promote medication adherence.

Key Words: sleep quality • HIV disease • women • depressive symptoms • medication adherence


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[Abstract] [PDF]