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The Diabetes Educator

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Clinical Nursing Research
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The Effect of Xanthines on Fluid Balance

Mary T. Martof

University of Southwestern Louisiana, mmarto{at}nomvs.lsumc.edu

Dorothy K. Knox

University of Southwestern Louisiana

To determine whether drinks containing caffeine and theophylline cause more fluid loss than equivalent amounts of non-xanthine drinks, convenience sample of 30 adults between the ages of 57 and 81 was selected Subjects were picked for 2 groups: those who had developed tolerance to these xanthines and used them freely (the X Group) and those who habitually omitted drinks containing xanthines from their diets (the NO X Group). Both groups consumed approximately 2 liters of fluid daily for 5 days. When overall means were compared by analysis of variance, the two groups did not differ on serum osmolality for Day 5, change in serum osmolality (from Day 0 to Day 5), adjusted I/0 ratio, percent weight change from Day 0, or percent weight change from previous day. Analysis of the same variables on a daily basis indicated that the X group was better hydrated on Day 4.

Clinical Nursing Research, Vol. 6, No. 2, 186-196 (1997)
DOI: 10.1177/105477389700600207
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